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Scaleable genomics platform where customers have full control.
Genomics Data Management
Codified Genomics offers a cutting-edge platform for the comprehensive management, rapid analysis and rapid reanalysis of large-scale genomic datasets.
New innovations based upon AI-driven genetic annotation, probabilistic modeling, and disease phenotype integration have been used to create the CODIFIED DATA ECOSYSTEM (CDE), a new generation of software approaches to rapidly identify disease-related genetic variants for clinical diagnostics and research, genomic labs, and biotech firms. The CDE accelerates discovery, improves diagnostic yield and reduces time to insight.
This does not constitute an endorsement
With over 24,000 exomes, over 40,000 gene panels and 2,000 whole genomes analyzed, the Codified Genomics process has experience at the heart of its development. Our software has enabled hundreds of analyses of exomes, the discovery of dozens of new disease mutations and the description of entirely novel diseases.
The most expensive component of genome sequencing is the time that professionals spend pouring over data. The Codified Genomics process streamlines and standardizes tertiary analysis enabling the clinician to make the most of her time.
Codified Genomics provides data from a multitude of sources on the variant, gene, pathway and local genomic levels and helps hone in on causative variants quickly and accurately; Codified Genomics puts a world of knowledge at the clinician's fingertips. Automated processes enable the report to be fully ACMG compliant without requiring the reviewer to tediously classify every variant, freeing them to do what's most important: improving lives.
Codified Genomics enables intelligent filtering and prioritization by gathering all salient information for the genomic coordinate, variant, gene model, protein, function, expression, disease, population and system-interactions. This data is compiled together with assay metrics to allow automatic filtering and prioritization of variants for a patient. The data is displayed simply and cleanly to let the user make the final choice about which variants are and are not important. Finally, this information is captured and used the next time a patient is reviewed to help make analysis faster and more accurate.
Codified was founded in 2013 by Matthew Bainbridge (Chief Executive Officer) and Eric Venner (Chief Technical Officer) from Baylor College of Medicine, to meet the challenge of the growing volume of genetic data emerging as a consequence of new genomic technologies. Codified initially developed and offered boutique services to academic and clinical customers, supporting both gene discovery and genetic reporting for selected clients.
Data Analysis
Get results that are timely, accurate, complete.
Prioritized genomic variant data: See what matters first.
Fully Automated: Spend less time on routine classification.
Easy to use: Get your team up and running faster and consistently
Interact: Get your team talking, to each other, and the clinician.
Finding disease causing variants is difficult and time consuming. Of the 100,000 variants typically discovered in an exome sequence, only a handful will have medical relevance. Codified Genomics sifts through these variants, hiding those that are unlikely to cause disease, prioritizing those that are left, and giving the user a wide array of data to help find the cause of disease.
For more information, see Our Products.
Codified Genomics facilitates the data needs of the user by keeping each and every variantdiscovered. With access to over 15,000 exomes and genomes from diverse populations, however, our process can quickly eliminate those variants which are too common, or likely artifacts from consideration. Using multiple models, Codified Genomics scores the deleteriousness of each variant, and combines that information with knowledge of the phenotype, gene, and disease alleles to score the variant. The data for each variant is summarized and presented in an easily viewed interface with quick access to full information at the click of your mouse.
To meet the needs of current and potential customers, Codified has evolved their software suite to a more comprehensive, large-scale data management system, improving the offering by incorporating novel AI driven approaches to genetic analysis, and providing solutions to new compliance requirements for genetic data. Codified initiated corporate restructuring, converting to a C-Corp in September 2025. Subsequent investment has enabled the completion of modules within the new CDE.